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Dr Julie Bruneau |
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By Richard Ashby and Dalila
Benhaberou-Brun
Stemming HIV transmission in
an at-risk population
The many dangers related to injection drug use, especially among
individuals who share needles with other users, are well known.
This practice opens the door to the transmission of serious
diseases, in particular HIV, and has consequences for the public in
general. However, a new study led by Dr Julie Bruneau, a CRCHUM
physician and researcher, has revealed that transmission rates have
declined among injection drug users (IDU) in
Montreal.
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Funded by the Canadian Institutes for Health Research, the United
States National
Institute on Drug Abuse and the Fonds de la recherche en
santé du Québec, this
epidemiological study shows that the rate of new HIV infections
among IDUs in Montreal
has gradually declined since 1992 but that the downward trend has
displayed a fourfold increase since 2001. “This finding
suggests a favourable impact of
Montreal’s needle distribution program,” notes Bruneau.
Drawing on observations of more
than 2,000 drug addicts between 1992 and 2008, the study also
revealed that needle
sharing, cocaine injection and unstable housing conditions are
among the main drivers
of the HIV epidemic among IDUs.
MONTREAL LEADING THE WAY
Montreal was among the first North American cities to set up needle
exchange programs
in the late 1980s. With support from public health authorities,
Montreal now has one of
the most liberal needle distribution programs in North America.
Based on an exchange
program, IDUs can obtain an unlimited number of syringes and other
injection materials
are supplied by community workers and by local community service
centres. Also, a
network of pharmacies that sell needles at low cost to IDUs was set
up.
THE ST.LUC COHORT — AN INDISPENSABLE RESOURCE
The observed decline in infections and its relationship to
Montreal’s HIV prevention
programs was made possible thanks to the existence of the St.Luc
Cohort. This cohort
has been recruiting IDUs since 1988, and over time has become one
of the only cohorts
in the world able to provide information about the natural history,
etiology,
transmission and pathogenesis of HIV and HCV in this population.
The research that it
enables benefits not only from a large pool of subjects but also
the possibility of
following them over long periods of time. The data obtained are
crucial to our understanding of
the transmission dynamics and the impact of interventions.They also
contribute to the
application of scientific knowledge to improving the health of the
population, as the
present recently published study reveals.
A WORD OF WARMING
Notwithstanding the observed progress, Bruneau is quick to point
out that the epidemic
has yet to be controlled: “Needle exchange and distribution
programs are not enough because
they have to be part of a larger strategy.” A better
understanding of the mechanisms of HIV
transmission allow for adjustments to be made to existing
measures. The results of Bruneau’s
study argue in favour of a diversity of means for reaching out to
and equipping IDUs, including
safe injection sites and innovative drug addiction treatment
programs.
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